Use SureBeads Protein G Magnetic Beads for fast, easy, and reliable bioseparations: immunoprecipitation (IP), co-immunoprecipitation (co-IP), and protein pull-down assays.

Superparamagnetic beads with surface-activated hydrophilic polymer and chemically conjugated protein A bind the Fc regions of immunoglobulins with high specificity.

• Faster IP using magnetization instead of centrifugation
• Unique bead surface chemistry ensures optimal antibody orientation for increased antigen binding efficiency
• High IgG binding affinity with low nonspecific binding and reduced antibody consumption
• Beads cling magnetically to the side wall of the tube, not the bottom, for easier wash pipetting

Packaging Options

Conjugated Protein	Bead Suspension Volume	Rack Size (Number of Tubes)	Catalog #
G	1 ml	—	161-4021
G	3 ml	—	161-4023
G	1 ml	4*	161-4821
A	1 ml	—	161-4011
A	3 ml	—	161-4013
A	1 ml	4*	161-4811
A/G	2 x 3 ml	16	161-4833
G/G	2 x 3 ml	16	161-4823
A/A	2 x 3 ml	16	161-4813
16-tube magnetic rack		16	161-4916

*Trial kit

Related Products

• Protein Electrophoresis and Western Blotting
• Protein Sample Preparation

More Information

Protein A and protein G have different binding affinities for various species and subclasses of monoclonal and polyclonal antibodies. Use the table below to select the best SureBeads products for your needs.

Protein A/G Immunoprecipitation Guide

Monoclonal	Protein A	Protein G
Human IgG1	+++	+++
Human IgG2	+++	+++
Human IgG3	–	+++
Human IgG4	+++	+++
Mouse IgG1	+	+++
Mouse IgG2a	+++	+++
Mouse IgG2b	++	++
Mouse IgG3	++	++
Rat IgG1	–	+
Rat IgG2aa	–	+++
Rat IgG2b	–	++
Rat IgG2c	+	++
Polyclonal	Protein A	Protein G
Rabbit	+++	++
Cow	++	+++
Horse	++	+++
Goat	–	++
Guinea pig	+++	++
Sheep	+/-	++
Pig	++	++
Rat	+/-	++
Mouse	++	++
Chicken	–	+
Human IgG	+++	+++
Human IgM	–	+
Human IgD	–	+
Human IgA	–	+

– No binding
+ Weak binding
++ Moderate binding
+++ Strong binding